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dnarXiv
Source_Encoding
Commits
058f9a87
Commit
058f9a87
authored
3 years ago
by
BOULLE Olivier
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decode test
parent
502af0ff
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1 changed file
sequence_control.py
+29
-6
29 additions, 6 deletions
sequence_control.py
with
29 additions
and
6 deletions
sequence_control.py
+
29
−
6
View file @
058f9a87
...
@@ -2,10 +2,14 @@ import sys
...
@@ -2,10 +2,14 @@ import sys
import
dna_file_reader
as
dfr
import
dna_file_reader
as
dfr
import
hashing
import
hashing
import
source_encoding
import
source_encoding
from
numpy
import
source
import
source_decoding
def
check_homopolymere
(
sequence
,
max_h
):
def
check_homopolymere
(
sequence
,
max_h
):
"""
count the number of homopolymeres in the sequence
"""
h_nbr
=
0
#number of homopolymere larger than h_max found
h_nbr
=
0
#number of homopolymere larger than h_max found
row_size
=
0
#size of the current row
row_size
=
0
#size of the current row
last_nucleotide
=
""
#previous nucleotide in the sequence
last_nucleotide
=
""
#previous nucleotide in the sequence
...
@@ -54,6 +58,9 @@ def check_GC(sequence, window_size):
...
@@ -54,6 +58,9 @@ def check_GC(sequence, window_size):
def
check_loop
(
sequence
,
loop_size
,
window_size
):
def
check_loop
(
sequence
,
loop_size
,
window_size
):
"""
count the number of potential loops (reverse complement of a sub sequence in a local window)
"""
loop_nbr
=
0
loop_nbr
=
0
if
len
(
sequence
)
<
2
*
loop_size
:
#sequence too short for any loop
if
len
(
sequence
)
<
2
*
loop_size
:
#sequence too short for any loop
return
0
return
0
...
@@ -67,7 +74,10 @@ def check_loop(sequence, loop_size, window_size):
...
@@ -67,7 +74,10 @@ def check_loop(sequence, loop_size, window_size):
return
loop_nbr
return
loop_nbr
def
sequence_check
(
sequence
,
window_size
,
verbose
=
False
):
def
sequence_check
(
sequence
,
window_size
=
60
,
verbose
=
False
):
"""
test if a the conditions for a correct sequence are met
"""
h_nbr
=
check_homopolymere
(
sequence
,
3
)
h_nbr
=
check_homopolymere
(
sequence
,
3
)
if
verbose
:
print
(
"
number of homopolymere larger than
"
,
3
,
"
:
"
,
h_nbr
)
if
verbose
:
print
(
"
number of homopolymere larger than
"
,
3
,
"
:
"
,
h_nbr
)
min_GC_percent
,
max_GC_percent
=
check_GC
(
sequence
,
window_size
)
min_GC_percent
,
max_GC_percent
=
check_GC
(
sequence
,
window_size
)
...
@@ -75,7 +85,7 @@ def sequence_check(sequence, window_size, verbose=False):
...
@@ -75,7 +85,7 @@ def sequence_check(sequence, window_size, verbose=False):
loop_nbr
=
check_loop
(
sequence
,
6
,
window_size
)
loop_nbr
=
check_loop
(
sequence
,
6
,
window_size
)
if
verbose
:
print
(
"
number of potential loop :
"
,
loop_nbr
)
if
verbose
:
print
(
"
number of potential loop :
"
,
loop_nbr
)
if
h_nbr
==
0
and
min_GC_percent
>
40
and
max_GC_percent
<
55
and
loop_nbr
==
0
:
if
h_nbr
==
0
and
min_GC_percent
>
=
40
and
max_GC_percent
<
=
55
and
loop_nbr
==
0
:
if
verbose
:
print
(
"
sequence is correct
"
)
if
verbose
:
print
(
"
sequence is correct
"
)
return
True
return
True
else
:
else
:
...
@@ -84,11 +94,13 @@ def sequence_check(sequence, window_size, verbose=False):
...
@@ -84,11 +94,13 @@ def sequence_check(sequence, window_size, verbose=False):
def
hash_until_correct
(
sequence
,
start_key
=
0
):
def
hash_until_correct
(
sequence
,
start_key
=
0
):
"""
use a hash on the sequence until it meets the conditions, return the hash key
"""
hash_key
=
start_key
hash_key
=
start_key
hash_filter
=
hashing
.
hash_string_to_formated_number
(
str
(
hash_key
),
len
(
sequence
),
4
)
hash_filter
=
hashing
.
hash_string_to_formated_number
(
str
(
hash_key
),
len
(
sequence
),
4
)
hashed_sequence
=
source_encoding
.
apply_filter
(
sequence
,
hash_filter
)
hashed_sequence
=
source_encoding
.
apply_filter
(
sequence
,
hash_filter
)
while
not
sequence_check
(
hashed_sequence
,
60
):
while
not
sequence_check
(
hashed_sequence
):
hash_key
+=
1
hash_key
+=
1
hash_filter
=
hashing
.
hash_string_to_formated_number
(
str
(
hash_key
),
len
(
sequence
),
4
)
hash_filter
=
hashing
.
hash_string_to_formated_number
(
str
(
hash_key
),
len
(
sequence
),
4
)
hashed_sequence
=
source_encoding
.
apply_filter
(
sequence
,
hash_filter
)
hashed_sequence
=
source_encoding
.
apply_filter
(
sequence
,
hash_filter
)
...
@@ -108,6 +120,16 @@ def find_hash_keys(sequence):
...
@@ -108,6 +120,16 @@ def find_hash_keys(sequence):
print
(
tot_hash
)
print
(
tot_hash
)
sequence_check
(
tot_hash
,
60
,
True
)
sequence_check
(
tot_hash
,
60
,
True
)
def
decode_poeme
(
sequence
):
hash_keys
=
[
2137
,
4123
,
1324
,
833
,
3
]
decoded_seq
=
""
for
i
in
range
(
5
):
sub_seq
=
sequence
[
200
*
i
:
200
*
(
i
+
1
)]
hash_filter
=
hashing
.
hash_string_to_formated_number
(
str
(
hash_keys
[
i
]),
200
,
4
)
decoded_sub_seq
=
source_decoding
.
remove_filter
(
sub_seq
,
hash_filter
)
decoded_seq
+=
decoded_sub_seq
print
(
decoded_seq
)
# =================== main ======================= #
# =================== main ======================= #
if
__name__
==
'
__main__
'
:
if
__name__
==
'
__main__
'
:
...
@@ -119,4 +141,5 @@ if __name__ == '__main__':
...
@@ -119,4 +141,5 @@ if __name__ == '__main__':
_
,
sequence
=
dfr
.
read_single_sequence_fasta
(
sequence_path
)
_
,
sequence
=
dfr
.
read_single_sequence_fasta
(
sequence_path
)
print
(
sequence_check
(
sequence
,
verbose
=
True
))
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