babel-node should not be used in production
As mentioned in the official documentation
Not meant for production use You should not be using babel-node in production. It is unnecessarily heavy, with high memory usage due to the cache being stored in memory. You will also always experience a startup performance penalty as the entire app needs to be compiled on the fly.
Check out the example Node.js server with Babel for an idea of how to use Babel in a production deployment.