Update front todo

infrared-bookchapter.tex

@@ -135,7 +135,7 @@ fontsize=\footnotesize
 
 \maketitle
 
-\TODO{Introduction still immature and incomplete. Check use of Vienna RNA package. Excursion 2 still needs to be written. Write last methods subsection about application-specific extensions (e.g. further constraints) and modifications(e.g. modified objective); example!?.}
+\TODO{Introduction still immature and incomplete. Check use of Vienna RNA package---ideally, most of the tutorial would not require the package (this certainly, does not work for all the negative design---so, we have to be careful how to communicate this and not to lock out all the Windows users). Write last methods subsection about application-specific extensions (e.g. further constraints) and modifications(e.g. modified objective); example!?.}
 
 \begin{abstract}
     Applications in biotechnology and bio-medical research call for effective strategies to design novel RNAs with very specific properties. Such advanced design tasks require support by computational design but at the same time put high demands on the flexibility of computational tools and their expressivity to model the applications-specific requirements. To address such demands, we present the computational framework \Infrared. It supports to develop advanced customized design tools, which generate designs with specific properties, often in a few lines of Python code.