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vidjil
vidjil
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f739dc6d
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f739dc6d
authored
Feb 17, 2021
by
Mathieu Giraud
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Merge branch 'doc/locus-update' into 'dev'
doc/locus.md: Update, length biais on RNA-Seq See merge request
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@@ -83,8 +83,9 @@ However, even as few as 50 bp well-centered on the CDR3 usually detect many reco
The key point, depending on the library preparation, is thus what position the CDR3 is actually in the read.
Anyway, with short reads, the identified recombinations may be skewed towards shorter sequences, such as:
-
more VJ than VDJ recombinations
-
shorter N and more deleted
V, J and possibly
D genes
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shorter N and more deleted D genes
Those biases could occur inside one locus but also favor loci/systems with shorter recombinations
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